Hermann is on the Missouri river at the crossroads of Highways 19 and 100. The Hermann Welcome Center is located at 312 Market Street (Highway 19), on the west side of the street, four blocks south of the Missouri River bridge.
From St. Louis/St. Charles County:
Take I-70 west to Highway 19 (Exit 175), go 15 miles south to Hermann.
From St. Louis/South St. Louis County:
Take I-44 west to Highway 100 (Exit 251), go west 38 miles to Hermann.
From Springfield/ Fort Leonard Wood area:
Take I-44 east to Highway 19 (Exit 208), go north 50 miles to Hermann.
From Kansas City/Columbia:
Take I-70 east to Highway 19 (Exit 175), go 15 miles south to Hermann.
From Jefferson City:
Take Highway 54 East to I-70 east, to Highway 19 (Exit 175), go 15 miles south to Hermann; or take Highway 94 to Highway 19, turn right (south) and go one mile into Hermann.
From the Katy Trail:
From McKittrick Trailhead take Highway 19 south 2 miles and use the protected bike lane to cross the Missouri River bridge into Hermann.